of the synthesisof oleic acid ().
Klenk E identified sphingomyelin as the stored phospholipid in cells frompatients with Niemann-Pick disease ().
Von Euler US identified a lipid-soluble substance from semen which stimulatesuterine smooth muscle contraction and named it prostaglandin ()
A specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids was discovered and its importance in the development of modern pathologies is demonstrated ().
Lipid metabolism - What is Life HOME
About 40% of the bodies caloric intake is derived from lipids and almost all of these calories come from fats, the . The fatty acid composition in terms of saturation (oxidation forms) is not uniform but varies with the origin. Plant fats contain more polyunsaturated fatty acids and animal fats contain more saturated fatty acids as well as cholesterol. Polyunsaturated fats are essential for humans because animals are not able to synthesize those on their own. Most lipids, however, have metabolic functions contributing to membrane structures and signaling. (C20:4) is a fatty acid which plays a central role as precursor for prostaglandin synthesis. Phospholipids are synthesized from diacylgycerolphosphate, a negatively charged phospholipid precursor and signaling molecule itself, carrying various hydrophilic and/or charged headgroups that determine the surface charge and chemical properties of biological membrane surfaces.