Generalized explanation of aerobic and anaerobic respiration:

Perhaps a few hundred million years after the first mitochondrion appeared, as the oceanic oxygen content, at least on the surface, increased as a result of oxygenic photosynthesis, those complex cells learned to use oxygen instead of hydrogen. It is difficult to overstate the importance of learning to use oxygen in respiration, called . Before the appearance of aerobic respiration, life generated energy via and . Because oxygen , aerobic respiration generates, on average, about per cycle as fermentation and anaerobic respiration do (although some types of anaerobic respiration can get ). The suite of complex life on Earth today would not have been possible without the energy provided by oxygenic respiration. At minimum, nothing could have flown, and any animal life that might have evolved would have never left the oceans because the atmosphere would not have been breathable. With the advent of aerobic respiration, became possible, as it is several times as efficient as anaerobic respiration and fermentation (about 40% as compared to less than 10%). Today’s food chains of several levels would be constrained to about two in the absence of oxygen. Some scientists have and oxygen and respiration in eukaryote evolution. is controversial.

Cellular respiration may best be described by the following equation: C6h1206+602-6CO2+6H20+36ATP.

An important evolutionary principle is organisms' developing a new feature for one purpose and then using that feature for other purposes as the opportunity arose. As complex life evolved in the newly oxygenated seafloors, several immediate survival needs had to be addressed. To revisit the , if an oxygen-dependent animal did not have access to oxygen, it meant immediate death. Obtaining oxygen would have been the salient requirement for early complex life that adopted aerobic respiration , which is how nearly all animals today respire. While animals in low-oxygen environments have adapted to other ways of respiring (or perhaps in the first place), they are all sluggish creatures and would have quickly lost in the coming arms race. , which is a critical connective tissue in animals, requires oxygen for its synthesis, and was one of numerous oxygen-dependencies that animals quickly adopted during the Cambrian Explosion.


Allows for more energetic respiration than anaerobic respiration.

Fermentation is a result of anaerobic respiration of the yeast in the

Since the most dramatic instances of speciation seem to have happened in the aftermath of mass extinctions, this essay will survey extinction first. A corollary to is that if any critical nutrient falls low enough, the nutrient deficiency will not only limit growth, but the organism will be stressed. If the nutrient level falls far enough, the organism will die. A human can generally survive between one and two months without food, ten days without water, and about three minutes without oxygen. For nearly all animals, all the food and water in the world are meaningless without oxygen. Some microbes can switch between aerobic respiration and fermentation, depending on the environment (which might be a very old talent), but complex life generally does not have that ability; nearly all aerobic complex life is oxygen dependent. The only exceptions are marine life which has adapted to . Birds can go where mammals cannot, , for instance, or being , due to their . If oxygen levels rise or fall very fast, many organisms will not be able to adapt, and will die.


Endosymbiotic Theory Introduction

Students apply this knowledge to an analysis of how the training effects of regular aerobic exercise contribute to an increase in muscle cells’ capacity for aerobic respiration. (NGSS)
Cell Division and GeneticsMitosis, Meiosis and Fertilization – Major Concepts, Common Misconceptions and Learning Activities (revised 11/2017)These teacher notes summarize important concepts concerning mitosis and meiosis and propose a sequence of learning activities that will help students learn and understand these concepts and progress beyond common misconceptions.

AP Biology Animations - Biology Junction

Given the predominant role of ubiquinone inoxidative respiration, the role that menaquinone plays inmitochondrial electron transfer is not well understood. However,menaquinone has an established electron carrier role in the ETC ofanaerobic bacteria and anaerobic mitochondria, and there isincreasing evidence regarding its possible role in tumormitochondria (,,,).In addition to the well known NADH-ubiquinone reductase activity ofmitochondrial complex I typical of aerobic respiration, there isalso a NADH-fumarate reductase anaerobic electron transport systemin mitochondria which is capable of using menaquinone to donateelectrons to run a reverse TCA conversion of fumarate to succinate(,). Elevation of TCA intermediates,fumarate and succinate, due to inactivation or deficiency offumarate hydratase in RCC serves as a prototypical onco-metabolicmechanism leading to HIFα stabilization that is a major drivingforce of RCC (,,).Elevated succinate can also lead to a novel post-translationalmodification called succination (), and the TERE1-interactingmitochondrial protein, TBL2, has been identified as a substrate forsuccination in RCC cells, although the consequence of thisalteration is unknown.