Cocaine Synthesis | Chemical Reactions | Organic …


Collect the lidocaine precipitate by vacuum filtration.
Rinse the solid with small portions of cold water and draw air through it to aid drying (Use high vacuum).
Allow this sample to air dry in your drawer until the next lab.
Calculate the final yield of your product.
Results
Chemical Reaction
Synthesis Of Lidocaine
Introduction
WHAT IS LIDOCAINE?
- C14H22N2O
is a crystalline compound that is used in the form of its hydrochloride as a
local anesthetic
and as an
arrhythmic agent.
- It is the first amino amide- type local anesthetic, was first synthesized under the name
xylocaine
by swedish chemist Nils Lofgren in 1943.
- Trade names for this substance include Xylocaine, Isocaine, and Anestacon, and its systematic chemical name is 2-(diethylamino)-N-(2’,6’-dimethylphenyl)acetamide.

A simplified total synthesis of the single enantiomers of cocaine and racemic cocaine is outlined

I sold / gave drugs to someone who then overdosed and died. What is going to happen? Many law enforcement agencies now aggressively investigate overdose deaths in order to build a case against the person(s) that provided the drug(s) to the deceased. If they are able to build a case (often through cell phone / text message records), the person providing the drugs may be charged with in some jurisdictions or simply with delivery of a controlled substance. Often times, the prosecutor will be seeking a substantial prison sentence with a threat of referring the case to federal court for prosecution (where the penalties are much more severe) under the so-called "Len Bias Law." What is STOP Court?


or by a combination of extraction and chemical synthesis: ..

The chemical nature of cocaine is such that it would be expected to appear in ..


What three roles does diethyl amine serve in this synthesis?

As a nucleophile to displace chloride anion from –CH2Cl in the α-chloro-2, 6-dimethylacetanilide by an SN2 type reaction;

As a base to absorb the HCl that is formed in the nucleophilic substitution reaction leading to lidocaine; and

As a solvent for the reaction.
3.